2244978-64-9
2244978-64-9
Chemical Structure
PSB-18422
- CAS No.: 2244978-64-9
- Formula:C12H9BrFNO4
- Molecular Weight:330.11
InChIKey: BRRVCURODGLQPJ-UHFFFAOYSA-N
SMILES: O=C(C1=C(CCC(O)=O)C2=C(C=C(C=C2F)Br)N1)O
Biological Activity: PSB-18422 is a GPR17 agonist, with an EC50 of 0.0279 μM for humans, 0.47 μM for rats, 0.753 μM for mice, and a human Ki of 1.46 μM. PSB-18422 triggers intracellular calcium mobilization via cross-species activation of GPR17. PSB-18422 can be used in the research of allergic bronchial inflammation[1].
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PSB-18422 | PSB-18422 is a GPR17 agonist, with an EC50 of 0.0279 μM for humans, 0.47 μM for rats, 0.753 μM for mice, and a human Ki of 1.46 μM. PSB-18422 triggers intracellular calcium mobilization via cross-species activation of GPR17. PSB-18422 can be used in the research of allergic bronchial inflammation. | |||||||||||||||||||||
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