2245074-20-6
2245074-20-6
Chemical Structure
HP1328
- CAS No.: 2245074-20-6
- Formula:C23H23N3O3
- Molecular Weight:389.45
IUPAC Name: 2-(2-methoxy-4-(((1-phenyl-1H-benzo[d]imidazol-5-yl)amino)methyl)phenoxy)ethan-1-ol
InChIKey: FNNZOQPZURDRII-UHFFFAOYSA-N
SMILES: OCCOC1=CC=C(CNC2=CC(N=CN3C4=CC=CC=C4)=C3C=C2)C=C1OC
Biological Activity: HP1328 is a potent inhibitor of FLT3 receptor tyrosine kinase (FLT3/ITD mutation). HP1328 is a benzoimidazole scaffold-based compound. HP1328 significantly reduces the leukemia burden and prolongs the survival of mice with FLT3/ITD leukemia[1].
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HP1328 | HP1328 is a potent inhibitor of FLT3 receptor tyrosine kinase (FLT3/ITD mutation). HP1328 is a benzoimidazole scaffold-based compound. HP1328 significantly reduces the leukemia burden and prolongs the survival of mice with FLT3/ITD leukemia. | |||||||||||||||||||||
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References
Keywords
