2245237-61-8

VUBI1 analogue-1 Chemical Structure
2245237-61-8

Chemical Structure

VUBI1 analogue-1

  • CAS No.: 2245237-61-8
  • Formula:C26H29BrClFN4O2
  • Molecular Weight:563.89

IUPAC Name: tert-butyl 6-(4-bromo-6-chloro-1-(4-fluoro-3,5-dimethylbenzyl)-1H-benzo[d]imidazol-2-yl)-2,6-diazaspiro[3.3]heptane-2-carboxylate

InChIKey: VXKBOSGNBGMADK-UHFFFAOYSA-N

SMILES: O=C(N1CC2(CN(C2)C3=NC4=C(N3CC5=CC(C)=C(F)C(C)=C5)C=C(Cl)C=C4Br)C1)OC(C)(C)C

Biological Activity: VUBI1 analogue-1 (compound 79) is a VUBI1 (HY-111671) analogue. VUBI1 (SOS1 activator 1) is a SOS1 activator with a Kd of 44 nM. VUBI1 analogue-1 can be used to synthesize (4S)-PROTAC SOS1 degrader-1 (HY-144657)[1].

Cat. No. Product Name Purity Description Pricing
HY-153606
VUBI1 analogue-1 98.94% VUBI1 analogue-1 (compound 79) is a VUBI1 (HY-111671) analogue. VUBI1 (SOS1 activator 1) is a SOS1 activator with a Kd of 44 nM. VUBI1 analogue-1 can be used to synthesize (4S)-PROTAC SOS1 degrader-1 (HY-144657).
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