2247210-09-7
2247210-09-7
Chemical Structure
YF438
- CAS No.: 2247210-09-7
- Formula:C23H26N4O5
- Molecular Weight:438.48
InChIKey: CXDJAWSOFCGCGY-UHFFFAOYSA-N
SMILES: O=C(CCCCCC(NO)=O)N(CC1=NOC(C2=CC=CC=C2)=N1)C3=CC=C(OC)C=C3
Biological Activity: YF438 is an HDAC inhibitor with effective anticancer activity both in vitro and in vivo. YF438 inhibits the growth and metastasis of triple-negative breast cancer (TNBC) cells by blocking the interaction between HDAC and MDM2, inducing the dissociation of MDM2-MDMX, and promoting the degradation of MDM2[1].
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YF438 | YF438 is an HDAC inhibitor with effective anticancer activity both in vitro and in vivo. YF438 inhibits the growth and metastasis of triple-negative breast cancer (TNBC) cells by blocking the interaction between HDAC and MDM2, inducing the dissociation of MDM2-MDMX, and promoting the degradation of MDM2. | |||||||||||||||||||||
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References
Keywords
