2254498-21-8
2254498-21-8
Chemical Structure
Vanin-1-IN-6
- CAS No.: 2254498-21-8
- Formula:C19H24N4O3
- Molecular Weight:356.42
InChIKey: UQONAEXHTGDOIH-AWEZNQCLSA-N
SMILES: O=C(N1C[C@@H](N2C(CCC2)=O)CC1)C3=CN=C(NC4(CCO5)CC4)C5=C3
Biological Activity: Vanin-1-IN-6 (Compound Ex. 26) is a potent Vanin-1 inhibitor with an IC50 of 0.2 nM. Vanin-1-IN-6 reduces cysteamine production by inhibiting the Vanin-1 enzyme, preventing oxidative stress caused by glutathione depletion, thereby alleviating tissue damage and inflammation. Vanin-1-IN-6 can be used in research on Vanin-related diseases (Crohn's disease, inflammation, and autoimmune diseases)[1].
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Vanin-1-IN-6 | Vanin-1-IN-6 (Compound Ex. 26) is a potent Vanin-1 inhibitor with an IC50 of 0.2 nM. Vanin-1-IN-6 reduces cysteamine production by inhibiting the Vanin-1 enzyme, preventing oxidative stress caused by glutathione depletion, thereby alleviating tissue damage and inflammation. Vanin-1-IN-6 can be used in research on Vanin-related diseases (Crohn's disease, inflammation, and autoimmune diseases). | |||||||||||||||||||||
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