2305154-31-6
2305154-31-6
Chemical Structure
JCN037
Synonym(s): JGK037
- CAS No.: 2305154-31-6
- Formula:C16H11BrFN3O2
- Molecular Weight:376.18
IUPAC Name: N-(3-bromo-2-fluorophenyl)-7,8-dihydro-[1,4]dioxino[2,3-g]quinazolin-4-amine
InChIKey: MTLUFWWVOINWEL-UHFFFAOYSA-N
SMILES: FC1=C(Br)C=CC=C1NC2=C3C=C(OCCO4)C4=CC3=NC=N2
Biological Activity: JCN037 (JGK037) is non-covalent and BBB-penetrant EGFR tyrosine kinase inhibitor, with IC50 values of 2.49 nM, 3.95 nM, 4.48 nM for EGFR, p-wtEGFR and pEGFRvⅢ, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JCN037 | 99.09% | JCN037 (JGK037) is non-covalent and BBB-penetrant EGFR tyrosine kinase inhibitor, with IC50 values of 2.49 nM, 3.95 nM, 4.48 nM for EGFR, p-wtEGFR and pEGFRvⅢ, respectively. | ||||||||||||||||||||
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References
Keywords
