2307311-19-7
Chemical Structure
TCO-GK-PEG4-NHS ester
- CAS No.: 2307311-19-7
- Formula:C33H52N4O14
- Molecular Weight:728.78
IUPAC Name: (22S)-22-(2-(((((Z)-cyclooct-4-en-1-yl)oxy)carbonyl)amino)acetamido)-1-((2,5-dioxopyrrolidin-1-yl)oxy)-1,16-dioxo-4,7,10,13-tetraoxa-17-azatricosan-23-oic acid
InChIKey: KPHXUINZEVPEKP-MJIISZSESA-N
SMILES: O=C(O)[C@H](CCCCNC(CCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)=O)NC(CNC(OC2CC/C=C\CCC2)=O)=O
Biological Activity: TCO-GK-PEG4-NHS ester is an ADC Linker, and can be used for synthesis of [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d. [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d binds with high affinity and immunoreactivity to HER2[1]. TCO-GK-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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TCO-GK-PEG4-NHS ester | TCO-GK-PEG4-NHS ester is an ADC Linker, and can be used for synthesis of [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d. [18F]AlF-NOTA-Tz-TCO-GK-2Rs15d binds with high affinity and immunoreactivity to HER2. TCO-GK-PEG4-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. | |||||||||||||||||||||
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Keywords
