2308548-54-9
2308548-54-9
Chemical Structure
MeOIstPyrd
- CAS No.: 2308548-54-9
- Formula:C14H16N4O2S
- Molecular Weight:304.37
InChIKey: UMNFROSIWNNARA-UHFFFAOYSA-N
SMILES: COC1=CC=C(NC(/C2=N\NC(N3CCCC3)=S)=O)C2=C1
Biological Activity: MeOIstPyrd is an anti-skin cancer agent. MeOIstPyrd inhibits cell proliferation, migration, and spheroid formation by activating the mitochondrial intrinsic apoptotic pathway. MeOIstPyrd induces DNA damage. MeOIstPyrd activates p53, and increases the half-life of p53 and stabilizes p53 by phosphorylating it at ser15. MeOIstPyrd binds to MDM2 in the p53 sub-pocket and blocks p53-MDM2 interaction[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MeOIstPyrd | 99.84% | MeOIstPyrd is an anti-skin cancer agent. MeOIstPyrd inhibits cell proliferation, migration, and spheroid formation by activating the mitochondrial intrinsic apoptotic pathway. MeOIstPyrd induces DNA damage. MeOIstPyrd activates p53, and increases the half-life of p53 and stabilizes p53 by phosphorylating it at ser15. MeOIstPyrd binds to MDM2 in the p53 sub-pocket and blocks p53-MDM2 interaction. | ||||||||||||||||||||
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