2353417-86-2
2353417-86-2
Chemical Structure
PROTAC VEGFR-2 degrader-3
- CAS No.: 2353417-86-2
- Formula:C55H66FN9O6S
- Molecular Weight:1000.23
InChIKey: YZGNCBAFOZBYKS-SHPBXJAASA-N
SMILES: NC1=NN(C(CCCCCCCCCCC(N[C@@H](C(C)(C)C)C(N2[C@@H](C[C@H](C2)O)C(NCC3=CC=C(C4=C(N=CS4)C)C=C3)=O)=O)=O)=O)C5=CC=CC(C6=CC=C(C=C6)NC(NC7=C(C=CC(C)=C7)F)=O)=C15
Biological Activity: VEGFR-2-IN-39 (PROTAC-5) is a PROTAC targeting VEGFR-2 (IC50: 208.6 nM). VEGFR-2-IN-39 has low toxicity.VEGFR-2-IN-39 inhibits the proliferation of EA.hy926, one of HUVECs, in a concentration-dependent manner, with an IC50 of 38.65 µM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PROTAC VEGFR-2 degrader-3 | 99.09% | VEGFR-2-IN-39 (PROTAC-5) is a PROTAC targeting VEGFR-2 (IC50: 208.6 nM). VEGFR-2-IN-39 has low toxicity.VEGFR-2-IN-39 inhibits the proliferation of EA.hy926, one of HUVECs, in a concentration-dependent manner, with an IC50 of 38.65 µM. | ||||||||||||||||||||
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Keywords
