2359662-39-6
Chemical Structure
ALK-IN-9
- CAS No.: 2359662-39-6
- Formula:C20H21FN6O3
- Molecular Weight:412.42
IUPAC Name: (R,14aE,15aE)-35-fluoro-13,6,6-trimethyl-13,14-dihydro-12H-4-oxa-7-aza-1(4,6)-pyrazolo[1',5':1,2]pyrimido[5,4-b][1,4]oxazina-3(3,2)-pyridinacyclooctaphan-8-one
InChIKey: KNGXEAMYHAUVNK-LLVKDONJSA-N
SMILES: O=C1NC(C)(COC2=C(CN3C4=NC5=C1C=NN5C=C4OC[C@H]3C)C=C(F)C=N2)C
Biological Activity: ALK-IN-9 (compound 40) is a potent ALK inhibitor. ALK-IN-9 inhibits cell proliferation with IC50s of <0.2 nM, <0.2 nM, 0.2 nM for Ba/F3-EML4-ALK, KM 12 (TPM3-TRKA), KG-l cell (OP2-FGFR1), respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
ALK-IN-9 | ALK-IN-9 (compound 40) is a potent ALK inhibitor. ALK-IN-9 inhibits cell proliferation with IC50s of <0.2 nM, <0.2 nM, 0.2 nM for Ba/F3-EML4-ALK, KM 12 (TPM3-TRKA), KG-l cell (OP2-FGFR1), respectively. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords