2361988-76-1
2361988-76-1
Chemical Structure
cRIPGBM
- CAS No.: 2361988-76-1
- Formula:C26H20FN2O2+
- Molecular Weight:411.45
IUPAC Name: 1-benzyl-3-(4-fluorobenzyl)-2-methyl-4,9-dioxo-4,9-dihydro-1H-naphtho[2,3-d]imidazol-3-ium
InChIKey: JICXOYDJADTPML-UHFFFAOYSA-N
SMILES: O=C(C1=C2[N+](CC3=CC=C(F)C=C3)=C(C)N1CC4=CC=CC=C4)C5=C(C=CC=C5)C2=O
Biological Activity: cRIPGBM, a proapoptotic derivative of RIPGBM, a cell type-selective inducer of apoptosis in GBM cancer stem cells (CSCs) by binding to receptor-interacting protein kinase 2 (RIPK2), with an EC50 of 68 nM in GBM-1 cells[1].
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cRIPGBM | cRIPGBM, a proapoptotic derivative of RIPGBM, a cell type-selective inducer of apoptosis in GBM cancer stem cells (CSCs) by binding to receptor-interacting protein kinase 2 (RIPK2), with an EC50 of 68 nM in GBM-1 cells. | |||||||||||||||||||||
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