2364554-48-1
2364554-48-1
Chemical Structure
Aficamten
Synonym(s): CK-274; CK-3773274
- CAS No.: 2364554-48-1
- Formula:C18H19N5O2
- Molecular Weight:337.38
IUPAC Name: (R)-N-(5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)-1-methyl-1H-pyrazole-4-carboxamide
InChIKey: IOVAZWDIRCRMTM-OAHLLOKOSA-N
SMILES: O=C(C1=CN(C)N=C1)N[C@H]2C3=CC=C(C4=NOC(CC)=N4)C=C3CC2
Biological Activity: Aficamten (CK-274) is a potent cardiac myosin inhibitor with an IC50 of 1.4 μM. Aficamten can be used for the research of hypertrophic cardiomyopathy (HCM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Aficamten | 99.86% | Aficamten (CK-274) is a potent cardiac myosin inhibitor with an IC50 of 1.4 μM. Aficamten can be used for the research of hypertrophic cardiomyopathy (HCM). | ||||||||||||||||||||
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Aficamten-d3 | Aficamten-d3 (CK-274-d3) is deuterium labeled Aficamten. Aficamten (CK-274) is a potent cardiac myosin inhibitor with an IC50 of 1.4 μM. Aficamten can be used for the research of hypertrophic cardiomyopathy (HCM). | |||||||||||||||||||||
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