2369068-46-0
2369068-46-0
Chemical Structure
Thalidomide-4-carbaldehyde
- CAS No.: 2369068-46-0
- Formula:C14H10N2O5
- Molecular Weight:286.24
IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindoline-4-carbaldehyde
InChIKey: QWOULBIWJJUUOD-UHFFFAOYSA-N
SMILES: O=CC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Biological Activity: Thalidomide-4-carbaldehyde is a Thalidomide analogue with an aldehyde. Thalidomide recruiits E3 ligase for the ubiquitinylation and subsequent proteolysis of target proteins. The aldehyde is highly reactive towards amine nucleophiles through reductive amination among other reactions.
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Thalidomide-4-carbaldehyde | Thalidomide-4-carbaldehyde is a Thalidomide analogue with an aldehyde. Thalidomide recruiits E3 ligase for the ubiquitinylation and subsequent proteolysis of target proteins. The aldehyde is highly reactive towards amine nucleophiles through reductive amination among other reactions. | |||||||||||||||||||||
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Keywords
