2376035-94-6
Chemical Structure
Drospirenone-d4
Synonym(s): Dihydrospirorenone-d4
- CAS No.: 2376035-94-6
- Formula:C24H26D4O3
- Molecular Weight:370.52
IUPAC Name: (4aR,4bS,6aS,7S,7aS,8aS,8bS,8cR,8dR,9aR)-4a,6a-dimethyl-3',4,4a,4b,4',5,6,6a,7a,8,8a,8b,8c,8d,9,9a-hexadecahydro-5'H-spiro[cyclopropa[4,5]cyclopenta[1,2-a]cyclopropa[l]phenanthrene-7,2'-furan]-2,5'(3H)-dione-3',3',4',4'-d4
InChIKey: METQSPRSQINEEU-MIWNBHHDSA-N
SMILES: C[C@@]12[C@](OC3=O)(C([2H])([2H])C3([2H])[2H])[C@@H](C4)[C@@H]4[C@@]1([H])[C@@]([C@@H]5[C@H]6C5)([H])[C@]([C@](C6=CC7=O)(CC7)C)([H])CC2
Biological Activity: Drospirenone-d4 is the deuterium labeled Drospirenone. Drospirenone (Dihydrospirorenone) is a synthetic progestin that is an analog to spironolactone[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Drospirenone-d4 | Drospirenone-d4 is the deuterium labeled Drospirenone. Drospirenone (Dihydrospirorenone) is a synthetic progestin that is an analog to spironolactone. | |||||||||||||||||||||
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Drospirenone (Standard) | 99.89% | Drospirenone (Standard) is the analytical standard of Drospirenone. This product is intended for research and analytical applications. | ||||||||||||||||||||
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Drospirenone-d4-1 | Drospirenone-d4-1 is deuterium labeled Drospirenone. | |||||||||||||||||||||
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Drospirenone-13C3 | Drospirenone-13C3 is 13C labeled Drospirenone. Drospirenone (Dihydrospirorenone) is a synthetic progesterone that is an analog of Spironolactone. | |||||||||||||||||||||
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Drospirenone | 99.95% | Drospirenone (Dihydrospirorenone) is an orally active fourth-generation progestin that interacts with the progesterone receptor (PR) and androgen receptor (AR). Drospirenone significantly decreases both plasminogen activator inhibitor-1 (PAI-1) and tissue plasminogen activator (tPA) via the AR. Drospirenone can produce DNA damage in bone marrow cells of female mice. . | ||||||||||||||||||||
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- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Fuhrmann, U., et al., The novel progestin drospirenone and its natural counterpart progesterone: biochemical profile and antiandrogenic potential. Contraception, 1996. 54(4): p. 243-51. [Content Brief]
