2378188-21-5
Chemical Structure
EGFR/C797S-IN-1
- CAS No.: 2378188-21-5
- Formula:C28H30N4O3
- Molecular Weight:470.56
IUPAC Name: 6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)-N-(4-phenoxyphenyl)quinazolin-4-amine
InChIKey: OGARAQZJFVUHBN-UHFFFAOYSA-N
SMILES: COC1=C(C=C2N=CN=C(C2=C1)NC3=CC=C(C=C3)OC4=CC=CC=C4)OCC5CCN(CC5)C
Biological Activity: EGFR/C797S-IN-1 is a potent EGFR-C797S inhibitor with an IC50 value of 0.128 µM. EGFR/C797S-IN-1 shows anti-proliferative activity and anti-tumor activity. EGFR/C797S-IN-1 inhibits the expression of p-EGFR in a dose-dependent manner[1].
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EGFR/C797S-IN-1 | EGFR/C797S-IN-1 is a potent EGFR-C797S inhibitor with an IC50 value of 0.128 µM. EGFR/C797S-IN-1 shows anti-proliferative activity and anti-tumor activity. EGFR/C797S-IN-1 inhibits the expression of p-EGFR in a dose-dependent manner. | |||||||||||||||||||||
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Keywords