2409072-27-9
2409072-27-9
Chemical Structure
HDAC6-IN-11
- CAS No.: 2409072-27-9
- Formula:C19H16N2O4
- Molecular Weight:336.34
IUPAC Name: (E)-N-hydroxy-3-(6-(4-methoxyphenoxy)quinolin-2-yl)acrylamide
InChIKey: VIDKIEAXAKFSHN-NYYWCZLTSA-N
SMILES: O=C(NO)/C=C/C1=NC2=CC=C(OC3=CC=C(OC)C=C3)C=C2C=C1
Biological Activity: HDAC6-IN-11 (Compound 9) is a selective HDAC6 inhibitor with the IC50 value of 20.7 nM. HDAC6-IN-11 has more than 300-fold selectivity over HDAC other isoforms. HDAC6-IN-11 shows anti-proliferative activities against cancer cells[1].
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HDAC6-IN-11 | HDAC6-IN-11 (Compound 9) is a selective HDAC6 inhibitor with the IC50 value of 20.7 nM. HDAC6-IN-11 has more than 300-fold selectivity over HDAC other isoforms. HDAC6-IN-11 shows anti-proliferative activities against cancer cells. | |||||||||||||||||||||
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