2411382-24-4
2411382-24-4
Chemical Structure
ASK1-IN-1
- CAS No.: 2411382-24-4
- Formula:C19H19N9O2
- Molecular Weight:405.41
IUPAC Name: N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-3-methoxy-1-(pyrazin-2-yl)-1H-pyrazole-4-carboxamide
InChIKey: FTPVMITWJIXRGQ-UHFFFAOYSA-N
SMILES: COC1=NN(C2=NC=CN=C2)C=C1C(NC3=NC(C4=NN=CN4C(C)C)=CC=C3)=O
Biological Activity: ASK1-IN-1 is a CNS-penetrant ASK1 (apoptosis signal-regulating kinase 1) inhibitor, with good potency (cell IC50=138 nM; Biochemical IC50=21 nM)[1].
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ASK1-IN-1 | 98.74% | ASK1-IN-1 is a CNS-penetrant ASK1 (apoptosis signal-regulating kinase 1) inhibitor, with good potency (cell IC50=138 nM; Biochemical IC50=21 nM). | ||||||||||||||||||||
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