2413029-40-8
2413029-40-8
Chemical Structure
EGFR-IN-89
- CAS No.: 2413029-40-8
- Formula:C26H31FN8O2S
- Molecular Weight:538.64
InChIKey: IGBZJJZEZHTAIC-UHFFFAOYSA-N
SMILES: FC1=CC(NC2=NC(NC3=C(N(C)S(=O)(C)=O)C=CC=C3)=C4C(NC=C4)=N2)=CC=C1N5CCN(CC)CC5
Biological Activity: EGFR-IN-89 (compound 13k) is a potent, fourth-generation EGFR mutation inhibitor with an IC50 of 10.1 nM against Del19/T790M/C797S mutations. EGFR-IN-89 shows higher selectivity over wild type[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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EGFR-IN-89 | 98.75% | EGFR-IN-89 (compound 13k) is a potent, fourth-generation EGFR mutation inhibitor with an IC50 of 10.1 nM against Del19/T790M/C797S mutations. EGFR-IN-89 shows higher selectivity over wild type. | ||||||||||||||||||||
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References
Keywords
