2413212-11-8

Afatinib N-Oxide Chemical Structure
2413212-11-8

Chemical Structure

Afatinib N-Oxide

  • CAS No.: 2413212-11-8
  • Formula:C24H25ClFN5O4
  • Molecular Weight:501.94

IUPAC Name: (S,E)-4-((4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-N,N-dimethyl-4-oxobut-2-en-1-amine oxide

InChIKey: IABSYXLQTGEUIV-CWDCEQMOSA-N

SMILES: ClC1=C(F)C=CC(NC2=NC=NC3=C2C=C(NC(/C=C/C[N+](C)([O-])C)=O)C(O[C@H]4CCOC4)=C3)=C1

Biological Activity: Afatinib N-Oxide is an impurity of Afatinib dimaleate in oxidative degradation. Afatinib dimaleate is an irreversible EGFR family inhibitor[1].

Cat. No. Product Name Purity Description Pricing
HY-133110
Afatinib N-Oxide Afatinib N-Oxide is an impurity of Afatinib dimaleate in oxidative degradation. Afatinib dimaleate is an irreversible EGFR family inhibitor.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References