2413649-89-3
2413649-89-3
Chemical Structure
HBV-IN-23
- CAS No.: 2413649-89-3
- Formula:C25H27N3O3S
- Molecular Weight:449.57
IUPAC Name: 2-(benzylthio)-6-(3-(dimethylamino)propoxy)-3-(furan-2-ylmethyl)quinazolin-4(3H)-one
InChIKey: ZBLVNGNLMSFJPS-UHFFFAOYSA-N
SMILES: CN(CCCOC1=CC=C2N=C(N(C(C2=C1)=O)CC3=CC=CO3)SCC4=CC=CC=C4)C
Biological Activity: HBV-IN-23 (Compound 5k) is an inhibitor of HBV DNA replication with an IC50 of 0.58 μM. HBV-IN-23 inhibits HBV DNA replication in both agent sensitive and resistant HBV strains. HBV-IN-23 shows anti-hepatocellular carcinoma cell (HCC) activities. HBV-IN-23 induces HepG2 cells apoptosis[1].
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HBV-IN-23 | HBV-IN-23 (Compound 5k) is an inhibitor of HBV DNA replication with an IC50 of 0.58 μM. HBV-IN-23 inhibits HBV DNA replication in both agent sensitive and resistant HBV strains. HBV-IN-23 shows anti-hepatocellular carcinoma cell (HCC) activities. HBV-IN-23 induces HepG2 cells apoptosis. | |||||||||||||||||||||
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