2413804-83-6
2413804-83-6
Chemical Structure
HPK1-IN-21
- CAS No.: 2413804-83-6
- Formula:C22H25ClFN5O2
- Molecular Weight:445.92
IUPAC Name: (1R,3S)-5'-(4-amino-3-(dimethylcarbamoyl)-2-fluorophenyl)-4'-chloro-3-methyl-1',2'-dihydrospiro[cyclopentane-1,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide
InChIKey: GZQHHAHIJAPECC-VXKWHMMOSA-N
SMILES: CN(C(C1=C(C(C2=C(C3=C(NC[C@@]34CC[C@](C(N)=O)(C4)C)N=C2)Cl)=CC=C1N)F)=O)C
Biological Activity: HPK1-IN-21 is a potent inhibitor of HPK1 kinase inhibitor (Ki=0.8 nM). HPK1-IN-21 also has orally active[1].
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HPK1-IN-21 | HPK1-IN-21 is a potent inhibitor of HPK1 kinase inhibitor (Ki=0.8 nM). HPK1-IN-21 also has orally active. | |||||||||||||||||||||
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References
Keywords
