2414373-42-3
2414373-42-3
Chemical Structure
RET-IN-21
- CAS No.: 2414373-42-3
- Formula:C19H16N6O
- Molecular Weight:344.37
IUPAC Name: 4-(5-((pyridin-4-ylmethyl)amino)pyrazolo[1,5-a]pyrimidin-3-yl)benzamide
InChIKey: DICBAYNNPUCOOQ-UHFFFAOYSA-N
SMILES: O=C(N)C1=CC=C(C2=C3N=C(NCC4=CC=NC=C4)C=CN3N=C2)C=C1
Biological Activity: RET-IN-21 (compound 5) is a selective RETV804M inhibitor with the IC50 of 0.02 μM. RET-IN-21 does not inhibit the wild type isoforms of RET or KDR. RET-IN-21 has antitumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
RET-IN-21 | 97.00% | RET-IN-21 (compound 5) is a selective RETV804M inhibitor with the IC50 of 0.02 μM. RET-IN-21 does not inhibit the wild type isoforms of RET or KDR. RET-IN-21 has antitumor activity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
