2414908-52-2
Chemical Structure
Adenylyl cyclase type 2 agonist-1
- CAS No.: 2414908-52-2
- Formula:C27H17BrClNO5
- Molecular Weight:550.78
IUPAC Name: (3S,3aR,6aS)-5'-bromo-5-(2-chlorophenyl)-3-(p-tolyl)-3a,6a-dihydrospiro[furo[3,4-c]pyrrole-1,2'-indene]-1',3',4,6(3H,5H)-tetraone
InChIKey: HVCLMGZGIMRDRV-LPOKKUQKSA-N
SMILES: [H][C@@]1(OC2([C@]3(C(N(C([C@@]13[H])=O)C4=CC=CC=C4Cl)=O)[H])C(C5=C(C2=O)C=CC(Br)=C5)=O)C6=CC=C(C=C6)C
Biological Activity: Adenylyl cyclase type 2 agonist-1 (Compound 73) is a potent agonist of adenylyl cyclase type 2 (AC2) with the EC50 of 90 nM. Adenylyl cyclase type 2 agonist-1 inhibits expression of Interleukin-6, making it a potential lead compound against respiratory diseases[1].
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Adenylyl cyclase type 2 agonist-1 | 99.37% | Adenylyl cyclase type 2 agonist-1 (Compound 73) is a potent agonist of adenylyl cyclase type 2 (AC2) with the EC50 of 90 nM. Adenylyl cyclase type 2 agonist-1 inhibits expression of Interleukin-6, making it a potential lead compound against respiratory diseases. | ||||||||||||||||||||
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Keywords