2415311-84-9
Chemical Structure
MMP-2/9-IN-1
- CAS No.: 2415311-84-9
- Formula:C14H16IN7S
- Molecular Weight:441.29
IUPAC Name: (E)-2-(1-(2-(2-((E)-4-iodobenzylidene)hydrazinyl)-4-methylthiazol-5-yl)ethylidene)hydrazine-1-carboximidamide
InChIKey: JRZPVQQAKYFXGY-ISUCCWLISA-N
SMILES: C/C(C1=C(C)N=C(N/N=C/C2=CC=C(I)C=C2)S1)=N\NC(N)=N
Biological Activity: MMP-2/9-IN-1 (Compound 4a) is a potent dual MMP-2 and MMP-9 inhibitor with IC50 values of 56 nM and 38 nM, respectively. MMP-2/9-IN-1 inhibits tumor growth, strongly induces cancer cell apoptosis, inhibits cell migration, and suppresses cell cycle progression leading to DNA fragmentation[1].
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MMP-2/9-IN-1 | MMP-2/9-IN-1 (Compound 4a) is a potent dual MMP-2 and MMP-9 inhibitor with IC50 values of 56 nM and 38 nM, respectively. MMP-2/9-IN-1 inhibits tumor growth, strongly induces cancer cell apoptosis, inhibits cell migration, and suppresses cell cycle progression leading to DNA fragmentation. | |||||||||||||||||||||
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Keywords
