2417117-84-9
Chemical Structure
AChE/Nrf2 modulator 1
- CAS No.: 2417117-84-9
- Formula:C27H27FN4O2
- Molecular Weight:458.53
IUPAC Name: 5-(3-((1-(3-fluorobenzyl)piperidin-4-yl)methoxy)phenyl)-3-(6-methylpyridin-3-yl)-1,2,4-oxadiazole
InChIKey: RRSJHXGJAMBCDJ-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=N1)C2=NOC(C3=CC(OCC4CCN(CC4)CC5=CC(F)=CC=C5)=CC=C3)=N2
Biological Activity: AChE/Nrf2 modulator 1 is an orally active acetylcholinesterase (AChE)/nuclear factor erythroid 2-related factor 2 (Nrf2) modulator. AChE/Nrf2 modulator 1 has Nrf2 inductive activity and AChE inhibitory activity for eeAChE and hAChE with IC50 values of 0.07 μM and 0.38 μM, respectively. AChE/Nrf2 modulator 1 can be used for the research of Alzheimer's disease[1].
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AChE/Nrf2 modulator 1 | AChE/Nrf2 modulator 1 is an orally active acetylcholinesterase (AChE)/nuclear factor erythroid 2-related factor 2 (Nrf2) modulator. AChE/Nrf2 modulator 1 has Nrf2 inductive activity and AChE inhibitory activity for eeAChE and hAChE with IC50 values of 0.07 μM and 0.38 μM, respectively. AChE/Nrf2 modulator 1 can be used for the research of Alzheimer's disease. | |||||||||||||||||||||
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