2417685-83-5
2417685-83-5
Chemical Structure
YLIU-4-105-1
- CAS No.: 2417685-83-5
- Formula:C32H34F3N7O2
- Molecular Weight:605.65
InChIKey: QXTJBILZOATCLN-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C2=NN3C=C(NC(C4CC4)=O)N=C3C=C2)=C(C)C=C1)NC5=CC(C(F)(F)F)=CC(CN6CCN(CC6)CC)=C5
Biological Activity: YLIU-4-105-1 is a Type II JAK2 inhibitor. YLIU-4-105-1 binds to the ATP-binding pocket of JH1. YLIU-4-105-1 has in vivo pharmacodynamic activity as evidenced by inhibiting pSTAT5, reducing spleen to body weight, and lowering blood reticulocyte counts in a dose-dependent manner[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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YLIU-4-105-1 | 99.39% | YLIU-4-105-1 is a Type II JAK2 inhibitor. YLIU-4-105-1 binds to the ATP-binding pocket of JH1. YLIU-4-105-1 has in vivo pharmacodynamic activity as evidenced by inhibiting pSTAT5, reducing spleen to body weight, and lowering blood reticulocyte counts in a dose-dependent manner. | ||||||||||||||||||||
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References
Keywords
