2428400-60-4
Chemical Structure
(S,R.S)-AHPC-PEG8-acid
- CAS No.: 2428400-60-4
- Formula:C42H66N4O14S
- Molecular Weight:883.06
IUPAC Name: (S)-3-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-2,2-dimethyl-5-oxo-7,10,13,16,19,22,25,28-octaoxa-4-azadotriacontan-32-oic acid
InChIKey: MDRGRZJHLSHYPG-YIYQUBJESA-N
SMILES: OC(CCCOCCOCCOCCOCCOCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)=O)=O
Biological Activity: (S, R, S)-AHPC-PEG8-acid is a synthetic PROTAC linker that incorporatess an E3 ligase ligand with a PEG8 linker to empower PROTAC drug R&D. PEG8 increases the compound's aqueous solubility. Acid group is reactive with amine containing molecule.
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(S,R.S)-AHPC-PEG8-acid | (S, R, S)-AHPC-PEG8-acid is a synthetic PROTAC linker that incorporatess an E3 ligase ligand with a PEG8 linker to empower PROTAC drug R&D. PEG8 increases the compound's aqueous solubility. Acid group is reactive with amine containing molecule. | |||||||||||||||||||||
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Keywords
