24342-68-5
Chemical Structure
BnO-PEG6-OH
- CAS No.: 24342-68-5
- Formula:C19H32O7
- Molecular Weight:372.45
IUPAC Name: 1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-ol
InChIKey: VVBQKDDPSXBMMZ-UHFFFAOYSA-N
SMILES: OCCOCCOCCOCCOCCOCCOCC1=CC=CC=C1
Biological Activity: BnO-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). BnO-PEG6-OH is also a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1][2].
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BnO-PEG6-OH | 99.88% | BnO-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). BnO-PEG6-OH is also a PEG-based PROTAC linker can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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- [1]. Shaoyun Xiang, et al. Antibody drug conjugate, intermediate, preparation method, pharmaceutical composition and uses there. Patent WO2016197946A1.
- [2]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. [Content Brief]
Keywords