2438637-64-8

GNE684 Chemical Structure
2438637-64-8

Chemical Structure

GNE684

  • CAS No.: 2438637-64-8
  • Formula:C23H24N6O3
  • Molecular Weight:432.48

IUPAC Name: (S)-N-((S)-7-methoxy-1-methyl-2-oxo-2,3,4,5-tetrahydro-1H-pyrido[3,4-b]azepin-3-yl)-5-phenyl-6,7-dihydro-5H-pyrrolo[1,2-b][1,2,4]triazole-2-carboxamide

InChIKey: JXFYROJRZJPKTQ-IRXDYDNUSA-N

SMILES: COC1=NC=C(N(C)C([C@@H](NC(C2=NN([C@H](C3=CC=CC=C3)CC4)C4=N2)=O)CC5)=O)C5=C1

Biological Activity: GNE684 is a potent inhibitor of potent receptor interacting protein 1 (RIP1), with mean Kiapp values of 21 nM, 189 nM and 691 nM for human mouse and rat RIP1, respectively[1].

Cat. No. Product Name Purity Description Pricing
HY-128585
GNE684 99.08% GNE684 is a potent inhibitor of potent receptor interacting protein 1 (RIP1), with mean Kiapp values of 21 nM, 189 nM and 691 nM for human mouse and rat RIP1, respectively.
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