2439096-06-5
2439096-06-5
Chemical Structure
VEGFR-2-IN-26
- CAS No.: 2439096-06-5
- Formula:C24H19F3N6O2
- Molecular Weight:480.44
IUPAC Name: N-methyl-4-((4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)amino)quinazoline-2-carboxamide
InChIKey: WYRDCQCFFPDLMM-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=CC(C(F)(F)F)=C1)NC2=CC=C(NC3=C4C=CC=CC4=NC(C(NC)=O)=N3)C=C2
Biological Activity: VEGFR-2-IN-26 (compound 5h) is a highly potent VEGFR-2 inhibitor with an IC50 value of 15.5 nM. VEGFR-2-IN-26 has good antiproliferative activity against the leukemic, non-small lung, CNS, ovarian, renal, prostate and breast cancer cells[1].
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VEGFR-2-IN-26 | VEGFR-2-IN-26 (compound 5h) is a highly potent VEGFR-2 inhibitor with an IC50 value of 15.5 nM. VEGFR-2-IN-26 has good antiproliferative activity against the leukemic, non-small lung, CNS, ovarian, renal, prostate and breast cancer cells. | |||||||||||||||||||||
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