2442519-59-5

THRX-144644 Chemical Structure
2442519-59-5

Chemical Structure

THRX-144644

  • CAS No.: 2442519-59-5
  • Formula:C26H28ClF2N7
  • Molecular Weight:512.00

IUPAC Name: 6-(3-(5-chloro-2,4-difluorophenyl)-1H-pyrazol-4-yl)-N-(2-(4-isopropylpiperazin-1-yl)ethyl)-1,5-naphthyridin-3-amine

InChIKey: ATWFNMAJIPYWCA-UHFFFAOYSA-N

SMILES: FC1=CC(F)=C(C2=NNC=C2C3=NC4=C(C=C3)N=CC(NCCN5CCN(C(C)C)CC5)=C4)C=C1Cl

Biological Activity: THRX-144644 is a Lung-restricted ALK5 inhibitor with an IC50 value of 0.14 nM. THRX-144644 avoids systemic toxicities associated with TGFβ pathway inhibition[1].

Cat. No. Product Name Purity Description Pricing
HY-150169 		THRX-144644 99.43% THRX-144644 is a Lung-restricted ALK5 inhibitor with an IC50 value of 0.14 nM. THRX-144644 avoids systemic toxicities associated with TGFβ pathway inhibition.
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