2442519-59-5
2442519-59-5
Chemical Structure
THRX-144644
- CAS No.: 2442519-59-5
- Formula:C26H28ClF2N7
- Molecular Weight:512.00
IUPAC Name: 6-(3-(5-chloro-2,4-difluorophenyl)-1H-pyrazol-4-yl)-N-(2-(4-isopropylpiperazin-1-yl)ethyl)-1,5-naphthyridin-3-amine
InChIKey: ATWFNMAJIPYWCA-UHFFFAOYSA-N
SMILES: FC1=CC(F)=C(C2=NNC=C2C3=NC4=C(C=C3)N=CC(NCCN5CCN(C(C)C)CC5)=C4)C=C1Cl
Biological Activity: THRX-144644 is a Lung-restricted ALK5 inhibitor with an IC50 value of 0.14 nM. THRX-144644 avoids systemic toxicities associated with TGFβ pathway inhibition[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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THRX-144644 | 99.43% | THRX-144644 is a Lung-restricted ALK5 inhibitor with an IC50 value of 0.14 nM. THRX-144644 avoids systemic toxicities associated with TGFβ pathway inhibition. | ||||||||||||||||||||
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