2444781-71-7
Chemical Structure
Cabamiquine succinate
Synonym(s): DDD107498 succinate; DDD-498 succinate; M5717 succinate
- CAS No.: 2444781-71-7
- Formula:C31H37FN4O6
- Molecular Weight:580.65
IUPAC Name: 6-fluoro-2-(4-(morpholinomethyl)phenyl)-N-(2-(pyrrolidin-1-yl)ethyl)quinoline-4-carboxamide succinate
InChIKey: OTKHBNSZSWWVRJ-UHFFFAOYSA-N
SMILES: OC(CCC(O)=O)=O.O=C(C1=CC(C2=CC=C(C=C2)CN3CCOCC3)=NC4=CC=C(C=C41)F)NCCN5CCCC5
Biological Activity: Cabamiquine (DDD107498) succinate is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite, with an EC50 of 1 nM against P. falciparum 3D7. Cabamiquine succinate inhibits protein synthesis by targeting eEF2/CaMKIII, with an EC50 of 2 nM for WT-PfeEF2[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cabamiquine succinate | 99.80% | Cabamiquine (DDD107498) succinate is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite, with an EC50 of 1 nM against P. falciparum 3D7. Cabamiquine succinate inhibits protein synthesis by targeting eEF2/CaMKIII, with an EC50 of 2 nM for WT-PfeEF2. | ||||||||||||||||||||
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