2451479-86-8
Chemical Structure
hCAIX-IN-6
- CAS No.: 2451479-86-8
- Formula:C18H12N2O4S
- Molecular Weight:352.36
IUPAC Name: (E)-3-(4-cyanophenyl)-N-(2,2-dioxidobenzo[e][1,2]oxathiin-6-yl)acrylamide
InChIKey: ARJYJMVBLZXLQL-VMPITWQZSA-N
SMILES: N#CC1=CC=C(C=C1)/C=C/C(NC2=CC3=C(OS(=O)(C=C3)=O)C=C2)=O
Biological Activity: Compounds 6b and 14g showed significant inhibitory effect on tumor related subtype HCA IX with low nanomolar potency, while 6k was effective on HCA XII. Compounds 6b, 14g and 6k can be considered as the leading molecules for the development of future cancer therapeutic drugs based on new mechanisms of action.
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hCAIX-IN-6 | Compounds 6b and 14g showed significant inhibitory effect on tumor related subtype HCA IX with low nanomolar potency, while 6k was effective on HCA XII. Compounds 6b, 14g and 6k can be considered as the leading molecules for the development of future cancer therapeutic drugs based on new mechanisms of action. | |||||||||||||||||||||
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