2454459-87-9
Chemical Structure
hMAO-B-IN-2
- CAS No.: 2454459-87-9
- Formula:C18H23NO3
- Molecular Weight:301.38
IUPAC Name: 7-((5-(methyl(prop-2-yn-1-yl)amino)pentyl)oxy)chroman-4-one
InChIKey: CLKPCTKGZGRHKG-UHFFFAOYSA-N
SMILES: C#CCN(CCCCCOC1=CC2=C(C(CCO2)=O)C=C1)C
Biological Activity: hMAO-B-IN-2 (compound 6j) is an orally active, potent, selective and BBB penetrated and competitive reversible hMAO-B inhibitor, with an IC50 of 4 nM. hMAO-B-IN-2 shows low toxicity and good neuroprotective effects in SH-SY5Y cell. hMAO-B-IN-2 can be used for alzheimer’s disease research[1]. hMAO-B-IN-2 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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hMAO-B-IN-2 | hMAO-B-IN-2 (compound 6j) is an orally active, potent, selective and BBB penetrated and competitive reversible hMAO-B inhibitor, with an IC50 of 4 nM. hMAO-B-IN-2 shows low toxicity and good neuroprotective effects in SH-SY5Y cell. hMAO-B-IN-2 can be used for alzheimer’s disease research. hMAO-B-IN-2 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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Keywords
