2468202-93-7
2468202-93-7
Chemical Structure
IIIM-1266
- CAS. Nr.: 2468202-93-7
- Formula:C15H18N2O3S
- Molecular Weight:306.38
IUPAC Name: N,N-diethyl-2-oxo-1,2,2a1,8a-tetrahydrobenzo[cd]indole-6-sulfonamide
InChIKey: OWLWPUQSPONTPV-UHFFFAOYSA-N
SMILES: O=S(C1=C2C(C3=CC=C2)C(NC3=O)C=C1)(N(CC)CC)=O
Biological Activity: IIIM-1266 is a NLRP3 inflammasome inhibitor. IIIM-1266 inhibits IL-1β release in mouse macrophages (J774A.1 cells) (IC50 = 2.3 μM) and significantly reduced the protein expression level of mature IL-1β. IIIM-1266 can be used for the study of inflammation[1].
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IIIM-1266 | IIIM-1266 is a NLRP3 inflammasome inhibitor. IIIM-1266 inhibits IL-1β release in mouse macrophages (J774A.1 cells) (IC50 = 2.3 μM) and significantly reduced the protein expression level of mature IL-1β. IIIM-1266 can be used for the study of inflammation. | |||||||||||||||||||||
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