2469279-00-1

Venetoclax N-oxide Chemical Structure
2469279-00-1

Chemical Structure

Venetoclax N-oxide

  • CAS No.: 2469279-00-1
  • Formula:C45H50ClN7O8S
  • Molecular Weight:884.44

IUPAC Name: 4-(3-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)carbamoyl)phenyl)-1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine 1-oxide

InChIKey: CICPMKALXAZATM-UHFFFAOYSA-N

SMILES: O=C(NS(=O)(C1=CC=C(NCC2CCOCC2)C([N+]([O-])=O)=C1)=O)C3=CC=C(N4CC[N+](CC5=C(C6=CC=C(Cl)C=C6)CC(C)(C)CC5)([O-])CC4)C=C3OC7=CN=C(NC=C8)C8=C7

Biological Activity: Venetoclax N-oxide is an impurity of Venetoclax. Venetoclax (ABT-199; GDC-0199) is a highly potent, selective and orally bioavailable Bcl-2 inhibitor with a Ki of less than 0.01 nM[1].

Cat. No. Product Name Purity Description Pricing
HY-133772
Venetoclax N-oxide 99.66% Venetoclax N-oxide is an impurity of Venetoclax. Venetoclax (ABT-199; GDC-0199) is a highly potent, selective and orally bioavailable Bcl-2 inhibitor with a Ki of less than 0.01 nM.
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