2470019-41-9
2470019-41-9
Chemical Structure
Aldose reductase-IN-6
- CAS No.: 2470019-41-9
- Formula:C20H16N4O2S
- Molecular Weight:376.43
IUPAC Name: (E)-4-(2-(2-((3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)methylene)hydrazinyl)thiazol-4-yl)benzonitrile
InChIKey: JGTBCKRXHWTUDP-WSDLNYQXSA-N
SMILES: N#CC1=CC=C(C2=CSC(N/N=C/C3=CC=C(OCCCO4)C4=C3)=N2)C=C1
Biological Activity: Aldose reductase-IN-6 (Compound 3) is a competitive aldose reductase (AR) inhibitor with an IC50 of 3.164 μM and a Ki of 0.018 μM. Aldose reductase-IN-6 exhibits no cytotoxicity against healthy cells[1].
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Aldose reductase-IN-6 | Aldose reductase-IN-6 (Compound 3) is a competitive aldose reductase (AR) inhibitor with an IC50 of 3.164 μM and a Ki of 0.018 μM. Aldose reductase-IN-6 exhibits no cytotoxicity against healthy cells. | |||||||||||||||||||||
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