2487649-73-8
Chemical Structure
Axl-IN-9
- CAS No.: 2487649-73-8
- Formula:C25H23N7O2
- Molecular Weight:453.50
IUPAC Name: N-(4-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide
InChIKey: IYCNZCSESFTJTK-UHFFFAOYSA-N
SMILES: CC1=C(C(N(N1C)C2=CC=CC=C2)=O)C(NC3=CC=C(C=C3)C4=CN(C5=C4C(N)=NC=N5)C)=O
Biological Activity: Axl-IN-9 (Example 10) is a potent AXL inhibitor, with an IC50 of 26 nM. Axl-IN-9 has excellent transmembrane properties. Axl-IN-9 exhibits excellent pharmacokinetic properties in an animal body. Axl-IN-9 can be used for the research of proliferative diseases, autoimmune diseases, allergic diseases, inflammatory diseases, transplant rejection, cancer, or other diseases in mammals[1].
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Axl-IN-9 | Axl-IN-9 (Example 10) is a potent AXL inhibitor, with an IC50 of 26 nM. Axl-IN-9 has excellent transmembrane properties. Axl-IN-9 exhibits excellent pharmacokinetic properties in an animal body. Axl-IN-9 can be used for the research of proliferative diseases, autoimmune diseases, allergic diseases, inflammatory diseases, transplant rejection, cancer, or other diseases in mammals. | |||||||||||||||||||||
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