2490442-13-0
2490442-13-0
Chemical Structure
HBP08
- CAS No.: 2490442-13-0
- Formula:C60H77N17O14
- Molecular Weight:1260.36
InChIKey: WZNKFDLREDUFAM-QJVRGZEFSA-N
SMILES: OC([C@H](CC1=CN=CN1)NC([C@H]([C@@H](C)CC)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC(CN)=O)CC2=CC=C(C=C2)O)=O)CC3=CN=CN3)=O)CC4=CC=C(C=C4)O)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O
Biological Activity: HBP08 is a selective inhibitor of CXCL12/HMGB1 interaction. HBP08 has a high affinity for HMGB1 (Kd=0.8 μM). HBP08 inhibits CXCL12-mediated cell migration[1].
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HBP08 | HBP08 is a selective inhibitor of CXCL12/HMGB1 interaction. HBP08 has a high affinity for HMGB1 (Kd=0.8 μM). HBP08 inhibits CXCL12-mediated cell migration. | |||||||||||||||||||||
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