2496687-04-6
Chemical Structure
Mal-amido-PEG5-alkyne
- CAS No.: 2496687-04-6
- Formula:C20H30N2O8
- Molecular Weight:426.46
InChIKey: AFUMSMRNGMGCCB-UHFFFAOYSA-N
SMILES: O=C1C=CC(N1CCNC(CCOCCOCCOCCOCCOCC#C)=O)=O
Biological Activity: Mal-amido-PEG5-alkyne is a PEG linker containing a maleimide group and an alkyne. The hydrophilic PEG spacer increases solubility in aqueous media. The alkyne group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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Mal-amido-PEG5-alkyne | Mal-amido-PEG5-alkyne is a PEG linker containing a maleimide group and an alkyne. The hydrophilic PEG spacer increases solubility in aqueous media. The alkyne group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. | |||||||||||||||||||||
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Keywords
