253119-91-4
Chemical Structure
RC-552
- CAS. Nr.: 253119-91-4
- Formula:C102H193N2O21P
- Molecular Weight:1814.60
IUPAC Name: (R)-1-(((2R,3R,4R,5S,6R)-6-(hydroxymethyl)-5-(phosphonooxy)-4-(((R)-3-(tetradecanoyloxy)tetradecanoyl)oxy)-2-(((2R,3S,4R,5R)-2,3,4-trihydroxy-6-oxo-5-((R)-3-(palmitoyloxy)tetradecanamido)hexyl)oxy)tetrahydro-2H-pyran-3-yl)amino)-1-oxotetradecan-3-yl stearate
InChIKey: QXIVZARPNYHWFE-IPBWSHJOSA-N
SMILES: CCCCCCCCCCCCCC(O[C@H](CCCCCCCCCCC)CC(O[C@@H]1[C@H]([C@@H](O[C@H](CO)[C@H]1OP(O)(O)=O)OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](C=O)NC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCCCCCC)=O)=O)NC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCCCCCCCC)=O)=O)=O)=O
Biological Activity: RC-552 is a novel synthetic glycolipid related in chemical structure to MLA. RC-552 induces delayed cardioprotective effects via an iNOS-dependent pathway. RC-552 attenuates myocardial stunning[1][2].
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RC-552 | RC-552 is a novel synthetic glycolipid related in chemical structure to MLA. RC-552 induces delayed cardioprotective effects via an iNOS-dependent pathway. RC-552 attenuates myocardial stunning. | |||||||||||||||||||||
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References
- [1]. Elliott GT, et al. The novel glycolipid RC-552 attenuates myocardial stunning and reduces infarct size in dogs. J Mol Cell Cardiol. 2000 Jul;32(7):1327-39. [Content Brief]
- [2]. Xi L, et al. Glycolipid RC-552 induces delayed preconditioning-like effect via iNOS-dependent pathway in mice. Am J Physiol. 1999 Dec;277(6):H2418-24. [Content Brief]
