2538528-11-7
2538528-11-7
Chemical Structure
Topoisomerase IIα-IN-3
- CAS No.: 2538528-11-7
- Formula:C29H20N6O2S
- Molecular Weight:516.57
IUPAC Name: N-(5-(1H-indol-2-yl)-1,3,4-thiadiazol-2-yl)-1-(4-methoxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxamide
InChIKey: LLQVYDJGSVIJDS-UHFFFAOYSA-N
SMILES: O=C(C1=CC2=C(C(C3=CC=C(OC)C=C3)=N1)NC4=C2C=CC=C4)NC5=NN=C(C(N6)=CC7=C6C=CC=C7)S5
Biological Activity: Topoisomerase IIα-IN-3 (Compound 12c) is a DNA intercalative topoisomerase-IIα inhibitor. Topoisomerase IIα-IN-3 arrests cell cycle at the G0/G1 phase and induces apoptosis[1].
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Topoisomerase IIα-IN-3 | Topoisomerase IIα-IN-3 (Compound 12c) is a DNA intercalative topoisomerase-IIα inhibitor. Topoisomerase IIα-IN-3 arrests cell cycle at the G0/G1 phase and induces apoptosis. | |||||||||||||||||||||
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