2565792-45-0
Chemical Structure
BCN-DOTA
- CAS No.: 2565792-45-0
- Formula:C29H46N6O9
- Molecular Weight:622.71
InChIKey: BNBPIYJUCNHXJH-BKFWDETESA-N
SMILES: O=C(NCCNC(OC[C@H]1[C@@]2([H])CCC#CCC[C@@]12[H])=O)CN3CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC3
Biological Activity: BCN-DOTA is a cyclooctyne-linked DOTA chelator. BCN-DOTA integrates BCN and DOTA, enabling conjugation with azide-functionalized groups via the click chemistry properties of BCN, while binding to metal ions through the coordination capacity of DOTA. BCN-DOTA can serve as a radionuclide-drug conjugate (RDC) to target specific biomolecules, cells or tissues after radiolabeling with zirconium-89. BCN-DOTA is applicable to research related to PET imaging and targeted therapy[1].
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BCN-DOTA | BCN-DOTA is a cyclooctyne-linked DOTA chelator. BCN-DOTA integrates BCN and DOTA, enabling conjugation with azide-functionalized groups via the click chemistry properties of BCN, while binding to metal ions through the coordination capacity of DOTA. BCN-DOTA can serve as a radionuclide-drug conjugate (RDC) to target specific biomolecules, cells or tissues after radiolabeling with zirconium-89. BCN-DOTA is applicable to research related to PET imaging and targeted therapy. | |||||||||||||||||||||
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Keywords
