2568279-34-3

PROTAC SMARCA2 degrader-10 Chemical Structure
2568279-34-3

Chemical Structure

PROTAC SMARCA2 degrader-10

  • CAS No.: 2568279-34-3
  • Formula:C55H60N10O5S
  • Molecular Weight:973.19

InChIKey: BPPPLUHNKCEATN-FDHDIXGFSA-N

SMILES: O=C(C1=CC=C(C2=CC=C(C=C2)CN3CCC(CC3)CN4C=C(C5=C(N)N=NC(C6=C(C=CC=C6)O)=C5)C=N4)C=C1)N[C@@H](C(C)(C)C)C(N7[C@@H](C[C@H](C7)O)C(NCC8=CC=C(C9=C(N=CS9)C)C=C8)=O)=O

Biological Activity: PROTAC SMARCA2 degrader-10 (compound I-507) is a PROTAC degrader targeting SMARCA2; it degrades SMARCA2 proteins in A549 cells with an DC50 <100 nM, and a maximum degradation rate (Dmax%) >90 after 24 h of treatment[1].

Cat. No. Product Name Purity Description Pricing
HY-159462 		PROTAC SMARCA2 degrader-10 PROTAC SMARCA2 degrader-10 (compound I-507) is a PROTAC degrader targeting SMARCA2; it degrades SMARCA2 proteins in A549 cells with an DC50 <100 nM, and a maximum degradation rate (Dmax%) >90 after 24 h of treatment.
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