2568903-91-1
2568903-91-1
Chemical Structure
CHIKV-IN-5
- CAS No.: 2568903-91-1
- Formula:C23H17N5OS2
- Molecular Weight:443.54
InChIKey: BPGHLYIECPPFTL-UHFFFAOYSA-N
SMILES: O=C(NC1=NC(C2=CC(NC3=CC=C(C=C3)C#N)=CC=C2)=CS1)C4=C(N=CC=C4)SC
Biological Activity: CHIKV-IN-5 (Compound 26) is a CHIKV inhibitor (EC90 = 0.45 μM). CHIKV-IN-5 inhibits CHIKV replication at a late stage in the virus life cycle by blocking structural protein translation. CHIKV-IN-5 has great in vitro mouse microsomal stability. CHIKV-IN-5 reduces footpad swelling and decreases virus dissemination to other tissues in mice infected with CHIKV[1].
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CHIKV-IN-5 | CHIKV-IN-5 (Compound 26) is a CHIKV inhibitor (EC90 = 0.45 μM). CHIKV-IN-5 inhibits CHIKV replication at a late stage in the virus life cycle by blocking structural protein translation. CHIKV-IN-5 has great in vitro mouse microsomal stability. CHIKV-IN-5 reduces footpad swelling and decreases virus dissemination to other tissues in mice infected with CHIKV. | |||||||||||||||||||||
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References
Keywords
