2570251-63-5

SIAIS001 Chemical Structure
2570251-63-5

Chemical Structure

SIAIS001

  • CAS No.: 2570251-63-5
  • Formula:C48H51N7O4
  • Molecular Weight:789.96

InChIKey: OGAOHACYLUBWJQ-UHFFFAOYSA-N

SMILES: N#CC1=CC(NC2=C3C(C4=C(C2(C)C)C=C(N5CCC(CC5)N6CCN(CCCC#CC7=CC=CC8=C7CN(C9C(NC(CC9)=O)=O)C8=O)CC6)C(CC)=C4)=O)=C3C=C1

Biological Activity: SIAIS001 is a CRBN-dependent ALK PROTAC degrader with a DC50 of 3.9 nM. SIAIS001 induces ALK protein degradation via the ubiquitin-proteasome system. SIAIS001 induces G1/S phase cell cycle arrest and inhibits proliferation of cancer cells. SIAIS001 can be used for the research of anaplastic large-cell lymphomas[1].

Cat. No. Product Name Purity Description Pricing
HY-171825 		SIAIS001 SIAIS001 is a CRBN-dependent ALK PROTAC degrader with a DC50 of 3.9 nM. SIAIS001 induces ALK protein degradation via the ubiquitin-proteasome system. SIAIS001 induces G1/S phase cell cycle arrest and inhibits proliferation of cancer cells. SIAIS001 can be used for the research of anaplastic large-cell lymphomas.
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