2576427-49-9
2576427-49-9
Chemical Structure
VS3
- CAS No.: 2576427-49-9
- Formula:C21H21N3O3
- Molecular Weight:363.41
InChIKey: BVPWSDUNVDLFKY-UHFFFAOYSA-N
SMILES: CC1=CC=CC=C1COC2=CC=C(C3C(C=NN4)=C4NC(C3)=O)C=C2OC
Biological Activity: VS3 is a YAP-TEAD interaction inhibitor. VS3 directly disrupts the interaction between YAP-TEAD by binding to TEAD4 Interface 3 (Kd = 6 μM) on the surface. VS3 exhibits anti-proliferative activity against HT29, HCT116, and A2780. VS3 can be used for research on colorectal adenocarcinoma and ovarian cancer[1].
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VS3 | VS3 is a YAP-TEAD interaction inhibitor. VS3 directly disrupts the interaction between YAP-TEAD by binding to TEAD4 Interface 3 (Kd = 6 μM) on the surface. VS3 exhibits anti-proliferative activity against HT29, HCT116, and A2780. VS3 can be used for research on colorectal adenocarcinoma and ovarian cancer. | |||||||||||||||||||||
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