2585561-36-8
Chemical Structure
PROTAC BRD4 Degrader-16
- CAS No.: 2585561-36-8
- Formula:C46H41N7O8
- Molecular Weight:819.86
IUPAC Name: 1-(3-methoxybenzyl)-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrrolo[3,2-c]quinolin-4-amine
InChIKey: AQPUUPNSVBDCBQ-UHFFFAOYSA-N
SMILES: CN1C=C(C2=C(C1=O)NC(C(NCC3=CC=C(C=C3)C(NCCCCNC4=C5C(N(C(C5=CC=C4)=O)C6CCC(NC6=O)=O)=O)=O)=O)=C2)C7=CC=CC=C7OC8=CC=CC=C8
Biological Activity: PROTAC BRD4 Degrader-16 is a BRD4 PROTAC degrader. PROTAC BRD4 Degrader-16 induces sustained degradation of both long and short isoforms of BRD4 in cancer cells, causes cell cycle arrest, and exhibits only extremely low apoptosis effects. PROTAC BRD4 Degrader-16 can be used in studies related to acute myeloid leukemia[1].
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PROTAC BRD4 Degrader-16 | PROTAC BRD4 Degrader-16 is a BRD4 PROTAC degrader. PROTAC BRD4 Degrader-16 induces sustained degradation of both long and short isoforms of BRD4 in cancer cells, causes cell cycle arrest, and exhibits only extremely low apoptosis effects. PROTAC BRD4 Degrader-16 can be used in studies related to acute myeloid leukemia. | |||||||||||||||||||||
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