2588-04-7
2588-04-7
Chemical Structure
Phorate sulfone
- CAS No.: 2588-04-7
- Formula:C7H17O4PS3
- Molecular Weight:292.38
IUPAC Name: O,O-diethyl S-((ethylsulfonyl)methyl) phosphorodithioate
InChIKey: YVPSNUIHHFTTRL-UHFFFAOYSA-N
SMILES: O=S(CSP(OCC)(OCC)=S)(CC)=O
Biological Activity: Phorate sulfone, Phorate metabolite, is an insecticide. Phorate sulfone shows inhibitory activity aainst acetylcholinesterase with an IC50 of 40 μM, leading to acetylcholine accumulation at cellular and subcellular levels. Phorate sulfone can be used for the research of severe phorate poisoning[1][2].
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Phorate sulfone | Phorate sulfone, Phorate metabolite, is an insecticide. Phorate sulfone shows inhibitory activity aainst acetylcholinesterase with an IC50 of 40 μM, leading to acetylcholine accumulation at cellular and subcellular levels. Phorate sulfone can be used for the research of severe phorate poisoning. | |||||||||||||||||||||
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References
- [1]. Kunlun W, et al. Case report: Treatment of severe phorate poisoning. Front Toxicol. 2025;7:1581362. Published 2025 May 9. [Content Brief]
- [2]. Chapman R A, et al. Biochemical and chemical transformations of phorate, phorate sulfoxide, and phorate sulfone in natural and sterile mineral and organic soil[J]. Journal of Economic Entomology, 1982, 75(1): 112-117.
Keywords
