25953-14-4
25953-14-4
Chemical Structure
5'-Deoxy-5‘-iodothymidine
- CAS No.: 25953-14-4
- Formula:C10H13IN2O4
- Molecular Weight:352.13
IUPAC Name: 1-((2R,4S,5S)-4-hydroxy-5-(iodomethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
InChIKey: LEQXAJKTJWCXEC-XLPZGREQSA-N
SMILES: O=C(C(C)=C1)NC(N1[C@@H]2O[C@H](CI)[C@@H](O)C2)=O
Biological Activity: 5′-Deoxy-5′-iodothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5'-Deoxy-5‘-iodothymidine | 5′-Deoxy-5′-iodothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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